{"id":2297,"date":"2020-03-23T10:06:43","date_gmt":"2020-03-23T10:06:43","guid":{"rendered":"https:\/\/www.gaitbetter.com\/?p=2297"},"modified":"2025-07-30T11:37:14","modified_gmt":"2025-07-30T11:37:14","slug":"neurorehabilitation-and-neural-repair-do-patients-with-parkinsons-disease-with-freezing-of-gait-respond-differently-than-those-without-to-treadmill-training-augmented-by-virtual-reality","status":"publish","type":"post","link":"https:\/\/www.gaitbetter.com\/de\/neurorehabilitation-and-neural-repair-do-patients-with-parkinsons-disease-with-freezing-of-gait-respond-differently-than-those-without-to-treadmill-training-augmented-by-virtual-reality\/","title":{"rendered":"Do Patients With Parkinson\u2019s Disease With Freezing of Gait Respond Differently Than Those Without to Treadmill Training Augmented by Virtual Reality?"},"content":{"rendered":"
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Neurorehabilitation and Neural Repair. 2020 May;34(5):440-449.<\/a><\/h6>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Esther M J Bekkers, Anat Mirelman, Lisa Alcock, Lynn Rochester, Freek Nieuwhof, Bastiaan R Bloem, Elisa Pelosin, Laura Avanzino, Andrea Cereatti, Ugo Della Croce, Jeffrey M Hausdorff, Alice Nieuwboer<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Date: March 23, 2020<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Overview<\/h4>

People with parkinson’s disease and freezing of gait (FOG+) are associated with more falls, postural instability, and cognitive impairment than people without freezing of gait (FOG\u2212).\u00a0<\/p>

Purpose:<\/strong><\/p>

The goal of this study is to conduct a secondary analysis of the V-TIME study, a randomized, controlled research study showing a greater reduction in falls after virtual reality treadmill training (TT + VR) as compared with usual treadmill walking (TT) in a mixed population of fallers. During treadmill interventions, we examined whether FOG+ and FOG- gained similar gains.<\/p>

Methods:\u00a0<\/strong><\/p>

A total of 77 FOG+ and 44 FOG\u2212 were randomly assigned to TT + VR or TT. A six-month follow-up was conducted as well as pre- and post-training assessments. Mini Balance Evaluation System Test (Mini-BEST) was used to assess postural stability. Fall records were kept. The New Freezing of Gait Questionnaire (NFOG-Q) and Trail Making Test (TMT-B) were also used.\u00a0<\/p>

Findings:\u00a0<\/strong><\/p>

Mini-BEST scores and the TMT-B improved in both groups after training (P = .001), irrespective of study arm and FOG subgroup. However, gains were not sustained at 6 months. In both FOG+ and FOG-, falls were reduced after TT + VR compared with TT (P = .008). In the FOG+ group, scores on the NFOG-Q didn’t change after both modes of training.<\/p>

Conclusions:\u00a0<\/strong><\/p>

While controlling for disease severity differences, treadmill walking (with or without VR) improved postural instability in both FOG+ and FOG- patients. Even in those with FOG, TT + VR reduced falls more than TT alone. Although postural instability, falls and FOG are related, they may be controlled by different mechanisms, as training did not help FOG.<\/p>

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tREAD THE PAPER<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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GaitBetter has implemented commercially the V-TIME academic research project, that has led to many of these papers.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

NEUROREHABILITATION AND NEURAL REPAIR<\/p>","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32],"tags":[],"class_list":["post-2297","post","type-post","status-publish","format-standard","hentry","category-publications"],"_links":{"self":[{"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/posts\/2297","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/comments?post=2297"}],"version-history":[{"count":4,"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/posts\/2297\/revisions"}],"predecessor-version":[{"id":69229,"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/posts\/2297\/revisions\/69229"}],"wp:attachment":[{"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/media?parent=2297"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/categories?post=2297"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.gaitbetter.com\/de\/wp-json\/wp\/v2\/tags?post=2297"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}